Gene information
Official symbol TNFRSF1B
Official full name TNF receptor superfamily member 1B
Gene type protein-coding gene
Chromosome1p36.22
Alias symbolTNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Previous symbolTNFR2
Gene familyCD molecules; Tumor necrosis factor receptor superfamily; MicroRNA protein coding host genes
Resources
Entrez Gene 7133
HGNC HGNC:11917
Ensembl ENSG00000028137
Vega OTTHUMG00000001829
UCSC uc001att.4
GO terms: 94 records
GO Description Category LogP Number of genes Detail
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002700 regulation of production of molecular mediator of immune response GO Biological Processes -19.7615296 26 More
GO:0002706 regulation of lymphocyte mediated immunity GO Biological Processes -13.7265777 21 More
GO:0002709 regulation of T cell mediated immunity GO Biological Processes -8.74858930 12 More
GO:0002819 regulation of adaptive immune response GO Biological Processes -16.0189388 24 More
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -14.6775052 22 More
GO:0003170 heart valve development GO Biological Processes -11.9253160 20 More
GO:0003176 aortic valve development GO Biological Processes -8.77845673 13 More
GO:0005035 death receptor activity GO Molecular Functions -4.72638472 4 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007507 heart development GO Biological Processes -29.3002557 91 More
GO:0007568 aging GO Biological Processes -23.5429582 29 More
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage GO Biological Processes -5.52642112 8 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010611 regulation of cardiac muscle hypertrophy GO Biological Processes -13.5611908 22 More
GO:0010720 positive regulation of cell development GO Biological Processes -17.713649 52 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0014013 regulation of gliogenesis GO Biological Processes -13.3514185 26 More
GO:0014015 positive regulation of gliogenesis GO Biological Processes -11.0528361 19 More
GO:0014741 negative regulation of muscle hypertrophy GO Biological Processes -8.77845673 13 More
GO:0014743 regulation of muscle hypertrophy GO Biological Processes -14.1608908 23 More
GO:0019221 cytokine-mediated signaling pathway GO Biological Processes -27.5840932 43 More
GO:0019955 cytokine binding GO Molecular Functions -19.1485102 24 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030424 axon GO Cellular Components -6.14132550 54 More
GO:0030667 secretory granule membrane GO Cellular Components -8.32957622 38 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0031625 ubiquitin protein ligase binding GO Molecular Functions -1.82192201 21 More
GO:0031641 regulation of myelination GO Biological Processes -3.81944625 9 More
GO:0031644 regulation of nervous system process GO Biological Processes -8.22607591 24 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032944 regulation of mononuclear cell proliferation GO Biological Processes -24.6915018 34 More
GO:0033209 tumor necrosis factor-mediated signaling pathway GO Biological Processes -6.18341292 8 More
GO:0034612 response to tumor necrosis factor GO Biological Processes -24.4651326 32 More
GO:0035579 specific granule membrane GO Cellular Components -4.58725293 14 More
GO:0042129 regulation of T cell proliferation GO Biological Processes -18.0871480 25 More
GO:0042176 regulation of protein catabolic process GO Biological Processes -8.45353494 23 More
GO:0042581 specific granule GO Cellular Components -15.6202777 22 More
GO:0043025 neuronal cell body GO Cellular Components -9.18558636 52 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043502 regulation of muscle adaptation GO Biological Processes -16.8828965 29 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044297 cell body GO Cellular Components -11.7206640 62 More
GO:0044389 ubiquitin-like protein ligase binding GO Molecular Functions -1.61071129 9 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045685 regulation of glial cell differentiation GO Biological Processes -7.97684638 17 More
GO:0045687 positive regulation of glial cell differentiation GO Biological Processes -7.00526019 12 More
GO:0045862 positive regulation of proteolysis GO Biological Processes -17.3242033 33 More
GO:0048471 perinuclear region of cytoplasm GO Cellular Components -8.50169248 66 More
GO:0048713 regulation of oligodendrocyte differentiation GO Biological Processes -5.35296451 10 More
GO:0048714 positive regulation of oligodendrocyte differentiation GO Biological Processes -3.64344566 6 More
GO:0050670 regulation of lymphocyte proliferation GO Biological Processes -22.6006415 32 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0050767 regulation of neurogenesis GO Biological Processes -15.7439029 55 More
GO:0050769 positive regulation of neurogenesis GO Biological Processes -12.1167088 37 More
GO:0050863 regulation of T cell activation GO Biological Processes -20.3209154 36 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051048 negative regulation of secretion GO Biological Processes -20.2278199 42 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051129 negative regulation of cellular component organization GO Biological Processes -13.1016989 75 More
GO:0051249 regulation of lymphocyte activation GO Biological Processes -22.6120519 46 More
GO:0051960 regulation of nervous system development GO Biological Processes -17.2202851 64 More
GO:0051962 positive regulation of nervous system development GO Biological Processes -13.2580156 43 More
GO:0060284 regulation of cell development GO Biological Processes -22.9455891 78 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070848 response to growth factor GO Biological Processes -40.6139195 102 More
GO:0071216 cellular response to biotic stimulus GO Biological Processes -28.1549742 59 More
GO:0071219 cellular response to molecule of bacterial origin GO Biological Processes -28.3848077 56 More
GO:0071222 cellular response to lipopolysaccharide GO Biological Processes -26.0381191 52 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0071356 cellular response to tumor necrosis factor GO Biological Processes -22.5666334 29 More
GO:0071363 cellular response to growth factor stimulus GO Biological Processes -39.8883675 98 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0090257 regulation of muscle system process GO Biological Processes -33.9441291 67 More
GO:0097190 apoptotic signaling pathway GO Biological Processes -11.7839485 23 More
GO:0097191 extrinsic apoptotic signaling pathway GO Biological Processes -9.74858067 13 More
GO:0097193 intrinsic apoptotic signaling pathway GO Biological Processes -4.54525889 10 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:0150077 regulation of neuroinflammatory response GO Biological Processes -14.4671881 13 More
GO:0150079 negative regulation of neuroinflammatory response GO Biological Processes -5.31723275 7 More
GO:1901214 regulation of neuron death GO Biological Processes -23.5458880 37 More
GO:1901215 negative regulation of neuron death GO Biological Processes -19.0527525 45 More
GO:1903053 regulation of extracellular matrix organization GO Biological Processes -8.17680088 15 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903531 negative regulation of secretion by cell GO Biological Processes -17.4034654 36 More
GO:1905314 semi-lunar valve development GO Biological Processes -10.3278393 15 More
KEGG pathways: 6 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04061 Viral protein interaction with cytokine and cytokine receptor KEGG Pathway -30.3399237 29 More
hsa04668 TNF signaling pathway KEGG Pathway -16.5384917 20 More
hsa04920 Adipocytokine signaling pathway KEGG Pathway -10.4150431 19 More
hsa05014 Amyotrophic lateral sclerosis KEGG Pathway -1.64954984 10 More
hsa05022 Pathways of neurodegeneration - multiple diseases KEGG Pathway -4.18311884 18 More
Drug-Gene interaction
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Related drugs: 6 records
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
tumor necrosis factor receptor superfamily member 1B proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Mielczarek-Palacz A et al. Wiad Lek. 2011
tumor necrosis factor receptor superfamily member 1B proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Carlsson AC et al. Atherosclerosis. 2018
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